3 курс / Патологическая физиология / Остеопороз

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149.Black D, Delmas P, Eastell R et al. Once-Yearly Zoledronic Acid for Treatment of Postmenopausal Osteoporosis. N Engl J Med. 2007 May 3;356(18):1809-22 DOI: 10.1056/NEJMoa067312

150.Boonen S, Reginster J, Kaufman J et al. Fracture Risk and Zoledronic Acid Therapy in Men with Osteoporosis. New England Journal of Medicine. 2012;367(18):1714-1723

151.Reid DM, Devogelaer JP, Saag K, Roux C, Lau CS, Reginster JY, Papanastasiou P, Ferreira A, Hartl F, Fashola T, Mesenbrink P, Sambrook PN; HORIZON investigators. Zoledronic acid and risedronate in the prevention and treatment of glucocorticoid-induced osteoporosis (HORIZON): a multicentre, double-blind, double-dummy, randomised controlled trial. Lancet. 2009 Apr 11;373(9671):1253-63. doi: 10.1016/S0140- 6736(09)60250-6

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153.McClung M, Miller P, Recknor C, Mesenbrink P, Bucci-Rechtweg C, Benhamou C. Zoledronic Acid for the Prevention of Bone Loss in Postmenopausal Women With Low Bone Mass. Obstetrics & Gynecology. 2009;114(5):999-1007. doi:10.1097/aog.0b013e3181bdce0a

154.Reid IR, Horne AM, Mihov B, Stewart A, Garratt E, Wong S, Wiessing KR, Bolland MJ, Bastin S, Gamble GD. Fracture Prevention with Zoledronate in Older Women with Osteopenia. N Engl J Med. 2018 Dec 20;379(25):2407-2416. doi: 10.1056/NEJMoa1808082

155.Cummings S, Martin J, McClung M et al. Denosumab for Prevention of Fractures in Postmenopausal Women With Osteoporosis. N Engl J Med. 2009 Aug 20;361(8):75665. doi: 10.1056/NEJMoa0809493. Epub 2009 Aug 11

156.Langdahl B, Teglbjærg C, Ho P et al. A 24-Month Study Evaluating the Efficacy and Safety of Denosumab for the Treatment of Men With Low Bone Mineral Density: Results From the ADAMO Trial. The Journal of Clinical Endocrinology & Metabolism. 2015;100(4):1335-1342. doi:10.1210/jc.2014-4079

157.Orwoll E, Teglbjærg C, Langdahl B et al. A Randomized, Placebo-Controlled Study of the Effects of Denosumab for the Treatment of Men with Low Bone Mineral Density. The Journal of Clinical Endocrinology & Metabolism. 2012;97(9):3161-3169. doi:10.1210/jc.2012-1569

158.Saag KG, Pannacciulli N, Geusens P, Adachi JD, Messina OD, Morales-Torres J, Emkey R, Butler PW, Yin X, Lems WF. Denosumab vs risedronate in glucocorticoidinduced osteoporosis: final results of a 24-month randomized, double-blind, doubledummy trial. Arthritis Rheumatol. 2019 Feb 28. doi: 10.1002/art.40874

159.Gnant M, Pfeiler G, Dubsky P et al. Adjuvant denosumab in breast cancer (ABCSG18): a multicentre, randomised, double-blind, placebo-controlled trial. The Lancet. 2015;386(9992):433-443. doi:10.1016/s0140-6736(15)60995-3

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160.Smith MR, Egerdie B, Hernández Toriz N, Feldman R, Tammela TL, Saad F, Heracek J, Szwedowski M, Ke C, Kupic A, Leder BZ, Goessl C; DenosumabHALT Prostate Cancer Study Group. Denosumab in men receiving androgen-deprivation therapy for prostate cancer. N Engl J Med. 2009 Aug 20;361(8):745-55. doi: 10.1056/NEJMoa0809003. Epub 2009 Aug 11.

161.Amiche MA, Albaum JM, Tadrous M, et al. Efficacy of osteoporosis pharmacotherapies in preventing fracture among oral glucocorticoid users: a network. Osteoporos Int. 2016 Jun;27(6):1989-98. doi: 10.1007/s00198-015-3476-4.

162.Benlidayi IC. Denosumab in the treatment of glucocorticoid-induced osteoporosis. Rheumatol Int. 2018 Nov;38(11):1975-1984. doi: 10.1007/s00296-018-4106-1.

163.Yamaguchi Y, Morita T, Kumanogoh A. The therapeutic efficacy of denosumab for the loss of bone mineral density in glucocorticoid-induced osteoporosis: a metaanalysis. Rheumatol Adv Pract. 2020 Mar 13;4(1):rkaa008. doi: 10.1093/rap/rkaa008.

164.Yanbeiy ZA, Hansen KE. Denosumab in the treatment of glucocorticoid-induced osteoporosis: a systematic review and meta-analysis. Drug Des Devel Ther. 2019 Aug 14;13:2843-2852. doi: 10.2147/DDDT.S148654.

165.Miller P, Bolognese M, Lewiecki E et al. Effect of denosumab on bone density and turnover in postmenopausal women with low bone mass after long-term continued, discontinued, and restarting of therapy: A randomized blinded phase 2 clinical trial. Bone. 2008;43(2):222-229. doi:10.1016/j.bone.2008.04.007

166.Mandema JW1, Zheng J, Libanati C, Perez Ruixo JJ. Time course of bone mineral density changes with denosumab compared with other drugs in postmenopausal osteoporosis: a dose-response-based meta-analysis.J Clin Endocrinol Metab. 2014 Oct;99(10):3746-55. doi: 10.1210/jc .2013-3795. Epub 2014 Jun 10

167.Brown J, Prince R, Deal C et al. Comparison of the Effect of Denosumab and Alendronate on BMD and Biochemical Markers of Bone Turnover in Postmenopausal Women With Low Bone Mass: A Randomized, Blinded, Phase 3 Trial*. Journal of Bone and Mineral Research. 2009;24(1):153-161. doi:10.1359/jbmr.0809010

168.Choi NK, Solomon DH, Tsacogianis TN, Landon JE, Song HJ, Kim SC.Comparative Safety and Effectiveness of Denosumab Versus Zoledronic Acid in Patients With Osteoporosis: A Cohort Study. J Bone Miner Res. 2016 Oct 13. doi: 10.1002/jbmr.3019.

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170.Tsai J, Uihlein A, Burnett-Bowie S et al. Comparative Effects of Teriparatide, Denosumab, and Combination Therapy on Peripheral Compartmental Bone Density, Microarchitecture, and Estimated Strength: the DATA-HRpQCT Study. J Bone Miner Res. 2014;30(1):39-45. doi:10.1002/jbmr.2315.

171.Broadwell A, Chines A, Ebeling PR, Franek E, Huang S, Smith S, Kendler D, Messina O, Miller PD. Denosumab Safety and Efficacy Among Participants in the FREEDOM Extension Study With Mild to Moderate Chronic Kidney Disease. J Clin Endocrinol Metab. 2021 Jan 23;106(2):397-409. doi: 10.1210/clinem/dgaa851. PMID: 33211870; PMCID: PMC7823314.

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173.Miller PD, Pannacciulli N, Brown JP, Czerwinski E, Nedergaard BS, Bolognese MA, Malouf J, Bone HG, Reginster JY, Singer A, Wang C, Wagman RB, Cummings SR. Denosumab or Zoledronic Acid in Postmenopausal Women With Osteoporosis Previously

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174.McClung M. Inhibition of RANKL as a treatment for osteoporosis: Preclinical and early clinical studies. Current Osteoporosis Reports. 2006;4(1):28-33. doi:10.1007/s11914-006-0012-7

175.Белая Ж.Е., Рожинская Л.Я. Новые направления в терапии остеопороза – применение моноклональных человеческих антител к RANKL (Деносумаб). Остеопороз и Остеопатии. 2011;2:19-22

176.Neer R, Arnaud C, Zanchetta J et al. Effect of Parathyroid Hormone (1-34) on Fractures and Bone Mineral Density in Postmenopausal Women With Osteoporosis. N Engl J Med. 2001 May 10;344(19):1434-41 DOI:10.1056/NEJM200105103441904

177.Orwoll E, Scheele W, Paul S et al. The Effect of Teriparatide [Human Parathyroid Hormone (1-34)] Therapy on Bone Density in Men With Osteoporosis. J Bone Miner Res. 2003;18(1):9-17. doi:10.1359/jbmr.2003.18.1.9.

178.Saag K, Shane E, Boonen S et al. Teriparatide or Alendronate in GlucocorticoidInduced Osteoporosis. N Engl J Med. 2007 Nov 15;357(20):2028-39 DOI:10.1056/NEJMoa071408

179.Saag K, Zanchetta J, Devogelaer J et al. Effects of teriparatide versus alendronate for treating glucocorticoid-induced osteoporosis: Thirty-six-month results of a randomized, double-blind, controlled trial. Arthritis & Rheumatism. 2009;60(11):33463355. doi:10.1002/art.24879

180.Liu CL, Lee HC, Chen CC, Cho DY. Head-to-head comparisons of bisphosphonates and teriparatide in osteoporosis: a meta-analysis. Clin Invest Med. 2017;40(3):E146-E157. doi: 10.25011/cim.v40i3.28394.

181.Wang YK, Qin SQ, Ma T, Song W, Jiang RQ, Guo JB, Li K, Zhang YM. Effects of teriparatide versus alendronate for treatment of postmenopausal osteoporosis: A metaanalysis of randomized controlled trials. Medicine (Baltimore). 2017;96(21):e6970. doi: 10.1097/MD.0000000000006970.

182.Kendler DL, Marin F, Zerbini CAF, et al. Effects of teriparatide and risedronate on new fractures in post-menopausal women with severe osteoporosis (VERO): a multicentre, double-blind, double-dummy, randomised controlled trial. Lancet. 2018 Jan 20;391(10117):230-240. doi: 10.1016/S0140-6736(17)32137-2

183.Body J, Gaich G, Scheele W et al. A Randomized Double-Blind Trial to Compare the Efficacy of Teriparatide [Recombinant Human Parathyroid Hormone (1–34)] with Alendronate in Postmenopausal Women with Osteoporosis. The Journal of Clinical Endocrinology & Metabolism. 2002;87(10):4528-4535. doi:10.1210/jc.2002-020334.

184.Hadji P, Zanchetta J, Russo L et al. Effect of teriparatide compared with risedronate on back pain and incident vertebral fractures in postmenopausal women with osteoporotic vertebral fractures. Bone. 2011;48:S82-S83. doi:10.1016/j.bone.2011.03.108.

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187.European Medicines Agency: Recommendation to restrict the use of Protelos/Osseor (strontium ranelate) 25 April 2013 EMA/258269/2013

188.European Medicines Agency: Protelos/Osseor (strontium ranelate) to remain available but with futher restrictions 15 April 2014 EMA 235924/2014. J Rheumatology. 2005;32:1556-1562.

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190.Adler R, El-Hajj Fuleihan G, Bauer D et al. Managing Osteoporosis in Patients on Long-Term Bisphosphonate Treatment: Report of a Task Force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2016;31(1):16-35. doi:10.1002/jbmr.2708

191.Black DM, Boonen S, Cauley JA, Cummings SR, Lippuner K, Leung PC, Martinez RLM, Ruzycky ME, Eastell R (2012a) Erratum: The effect of 3 versus 6 years of Zoledronic acid treatment of osteoporosis: A randomized extension to the horizon-pivotal fracture trial (PFT). J Bone Miner Res 27(12):2612,

192.Black DM, Reid IR, Cauley JA, Cosman F, Leung PC, Lakatos P, Lippuner K, Cummings SR, Hue TF, Mukhopadhyay A, Tan M, Aftring RP, Eastell R (2015) The effect of 6 versus 9 years of zoledronic acid treatment in osteoporosis: A randomized second extension to the HORIZON-pivotal fracture trial (PFT). J Bone Miner Res 30(5): 934-944

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194.Bone HG, Wagman RB, Brandi ML, Brown JP, Chapurlat R, Cummings SR, Czerwiński E, Fahrleitner-Pammer A, Kendler DL, Lippuner K, Reginster JY, Roux C, Malouf J, Bradley MN, Daizadeh NS, Wang A, Dakin P, Pannacciulli N, Dempster DW, Papapoulos S. 10 years of denosumab treatment in postmenopausal women with osteoporosis: results from the phase 3 randomised FREEDOM trial and openlabel extension. Lancet Diabetes Endocrinol 2017 5(7):513-23

195.Bone HG, Bolognese MA, Yuenn CK, Kendler DL, Miller PD, Yang YC, Grazette L, Martin JS, Gallagher JC (2011) Effects of denosumab treatment and discontinuation on bone mineral density and bone turnover markers in postmenopausal women with low bone mass. J Clin Endocrinol Metab 96(4):972980

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200.Popp A, Zysset P, Lippuner K. Rebound-associated vertebral fractures after discontinuation of denosumab—from clinic and biomechanics. Osteoporosis International. 2015;27(5):1917-1921. doi:10.1007/s00198-015-3458-6.

201.Tsourdi E, Langdahl B, Cohen-Solal M, Aubry-Rozier B, Eriksen EF, Guanabens N, Obermayer-Pietsch B, Ralston SH, Eastell R, Zillikens MC. Discontinuation of denosumab therapy for osteoporosis: a systematic review and position statement by ECTS. Bone. 2017;105:11–17.

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